发明名称 ANTIBODY THERAPEUTICS WITH LOCAL ACTIVITY IN THE DIGESTIVE TRACT
摘要 This invention provides methods and compositions of antibody therapeutics that are therapeutically effective in the digestive tract or below the mucosal barrier of the digestive tract but do not deliver levels of antibody to the systemic circulation that have been shown to be necessary for clinical benefit following systemic administration of antibody. This invention further describes therapeutic compositions of antibody therapeutics that are therapeutically effective in the digestive tract or below the mucosal barrier of the digestive tract but do no deliver levels of antibody to the systemic circulation that have been associated with adverse events and systemic immunosuppression following systemic administration of antibody.
申请公布号 HK1173973(A1) 申请公布日期 2016.02.26
申请号 HK20130101231 申请日期 2013.01.29
申请人 AVAXIA BIOLOGICS INC. 发明人 BARBARA S. FOX;DOUGLAS C. STAFFORD
分类号 A61K;A61P;C07K 主分类号 A61K
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