| 摘要 |
Previously known methods for the synthesis of benzamide compounds and derivatives involved unstable intermediates, inefficient processes and, in some cases, a large number of steps, resulting in lower yields and increased costs of manufacturing. The present invention provides novel compounds, including compounds of Formula (I), wherein R1 is selected from Br and CN; R2 is selected from H and Br; R3 is H or -(C=X)R, wherein R is selected from H, CH3, CF3, CF2H, CFH2, CCl3, CCl2H, CClH2, CBr3, CBr2H and CBrH2; X is 0 or S, which compounds are useful in methods for the synthesis of benzamide compounds comprising fewer and/or more efficient steps, fewer isolations, higher yields, and improved purity. |
