The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of the peptide boronic acid proteasome inhibitor bortezomib.
申请公布号
SG10201600029P(A)
申请公布日期
2016.02.26
申请号
SG10201600029P
申请日期
2005.03.24
申请人
MILLENNIUM PHARMACEUTICALS, INC.
发明人
PICKERSGILL, I., FRASER;BISHOP, JOHN;KOELLNER, CHRISTOPH;GOMEZ, JEAN-MARC;GEISER, ACHIM;HETT, ROBERT;AMMOSCATO, VINCE;MUNK, STEPHEN;LO, YOUNG;CHUI, FANG-TING;KULKARNI, VITHALANAND, R.
