| 发明名称 |
MODULATORS OF PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR TREATMENT OF DISORDERS RELATED THERETO |
| 摘要 |
PROBLEM TO BE SOLVED: To provide modulators of prostacyclin (PGI2) receptor useful for treatment of disorders related thereto.SOLUTION: The present invention provides compounds represented by formula (XIIIa) or pharmacologically acceptable salts, solvates or hydrates thereof (where R1 and R2 independently represent H, aryl, heteroaryl or the like; X is O or NR3; R3 is H or C1-C6 alkyl; Q is OH, 1-carboxyethylamino or the like).SELECTED DRAWING: None |
| 申请公布号 |
JP2016028062(A) |
申请公布日期 |
2016.02.25 |
| 申请号 |
JP20150174518 |
申请日期 |
2015.09.04 |
| 申请人 |
ARENA PHARMACEUTICALS INC |
发明人 |
THUY-ANH TRAN;CHEN WEICHAO;BRYAN A KRAMER;ABU J M SADEQUE;HANNA L SHYFRYNA;SHIN YOUNG-JUN;PUREZA VALLAR;ZOU NING |
| 分类号 |
C07C275/24;A61K31/192;A61K31/27;A61K31/381;A61K31/426;A61K31/44;A61K31/4402;A61K31/4406;A61K31/4965;A61P1/04;A61P3/10;A61P7/02;A61P9/00;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/12;A61P17/06;A61P17/10;A61P19/02;A61P25/00;A61P25/02;A61P27/02;A61P27/06;A61P29/00;A61P31/04;A61P37/02;A61P37/06;A61P43/00;C07C271/12;C07C271/28;C07C275/28;C07C275/30;C07C275/34;C07D213/75;C07D241/20;C07D277/48;C07D333/36 |
主分类号 |
C07C275/24 |
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