Beta-HYDROXY-Beta-METHYLBUTYRIC ACID PURIFICATION METHOD

摘要

The present invention relates to a method for purifying β-hydroxyl-β-methyl butyrate, comprising neutralizing a crude β-hydroxyl-β-methyl butyrate with a base to produce a salt of β-hydroxyl-β-methyl butyrate, cooling and crystallizing, dissolving and acidifying, and extracting to obtain β-hydroxyl-β-methyl butyrate of high purity. No strict conditions, such as high temperature and high vacuum, are required in this method. On the contrary, it has low requirement on the apparatus, the process can readily be controlled and a product with high purity can be produced.

主权项

1. A method for purifying β-hydroxyl-β-methyl butyrate, comprising:
(1) Neutralizing a crude β-hydroxyl-β-methyl butyrate with a base, crystallizing, centrifuging, and drying to obtain a crystallized product containing a salt of β-hydroxyl-β-methyl butyrate; (2) Adding an inorganic acid to the product obtained in step (1) for dissolution and acidification, and extracting β-hydroxyl-β-methyl butyrate from the dissolved and acidified product to obtain β-hydroxyl-β-methyl butyrate of high purity.