| 发明名称 |
NEPRILYSIN INHIBITORS |
| 摘要 |
PROBLEM TO BE SOLVED: To provide neprilysin inhibitors.SOLUTION: The present invention provides a compound of the formula or a pharmacologically acceptable salt thereof (where Ris -ORor -NRR; Ris H or the like; X is (substituted) C1-9 heteroaryl for both Rand R; and R-Rare H, C1-8 alkyl or the like).SELECTED DRAWING: None |
| 申请公布号 |
JP2016028089(A) |
申请公布日期 |
2016.02.25 |
| 申请号 |
JP20150186389 |
申请日期 |
2015.09.24 |
| 申请人 |
THERAVANCE BIOPHARMA R&D IP LLC |
发明人 |
GENDRON ROLAND;MELISSA FLEURY;ADAM D HUGHES |
| 分类号 |
C07D231/14;A61K31/341;A61K31/381;A61K31/41;A61K31/415;A61K31/4155;A61K31/4162;A61K31/4192;A61K31/4196;A61K31/42;A61K31/421;A61K31/422;A61K31/423;A61K31/426;A61K31/437;A61K31/44;A61K31/4439;A61K31/454;A61K31/455;A61K31/4965;A61K31/497;A61K31/50;A61K31/505;A61K31/5365;A61K31/5377;A61K31/553;A61K45/00;A61P9/04;A61P9/12;A61P13/12;A61P43/00;C07C229/34;C07C271/22;C07D213/81;C07D237/04;C07D237/24;C07D239/28;C07D239/36;C07D241/24;C07D249/04;C07D249/10;C07D249/12;C07D249/18;C07D257/04;C07D261/18;C07D263/34;C07D263/56;C07D271/06;C07D271/07;C07D277/46;C07D307/68;C07D333/40;C07D401/04;C07D401/06;C07D403/04;C07D403/06;C07D403/12;C07D405/04;C07D405/12;C07D409/04;C07D413/04;C07D471/04;C07D498/04;C07D498/08 |
主分类号 |
C07D231/14 |
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