发明名称 |
ACID-ADDITION SALT OF Trk-INHIBITING COMPOUND |
摘要 |
In order to provide an agent for the prevention and/or treatment of Trk-related diseases, the present invention provides a compound that has selective inhibitory activity on Trk, persistently suppresses NGF vascular hyperpermeability, has no drug interactions, and also has exceptional absorbability and solubility in free bases. The compound of the present invention has selective inhibitory activity on Trk, persistently suppresses NGF vascular hyperpermeability, has no drug interactions, and has exceptional absorbability and solubility in free bases, and is therefore useful as a drug for the prevention and/or treatment of Trk-related diseases. |
申请公布号 |
WO2016027754(A1) |
申请公布日期 |
2016.02.25 |
申请号 |
WO2015JP72990 |
申请日期 |
2015.08.17 |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
TAKEUCHI, JUN;ITADANI, SATOSHI;IKURA, MASAHIRO;HIGASHINO, MASATO;KIJIMA, HIDEOMI;ONO, SHIZUKA;YASUHIRO, TETSUYA;NAGAURA, TAKESHI |
分类号 |
C07D401/12;A61K31/506;A61K45/00;A61P1/04;A61P11/02;A61P13/02;A61P17/04;A61P17/06;A61P25/02;A61P25/06;A61P29/00;A61P35/00;A61P37/08;A61P43/00;C07D401/14 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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