SOLUBLE AND DISPERSIBLE PHARAMACEUTICAL DEFERASIROX FORMULATION
摘要
The present invention relates to a soluble and dispersible pharmaceutical composition for oral administration comprising deferasirox. More specifically, the present invention relates to a soluble and dispersible pharmaceutical composition for oral administration comprising deferasirox and sodium carbonate or sodium bicarbonate or their mixture as an alkali agent in an acceptable carrier such that the said composition has a pH of 7.4-10.0 when dispersed in 100ml or 200ml water at 25°C, and solubility of deferasirox greater than 0.04 mg/ml.