| 摘要 |
Provided is a method with which it is possible to determine, at an initial stage of differentiation, the state of differentiation of undifferentiated stem cells. The present invention relates to: "a method for determining the state of differentiation of a cell by detecting the expression of a <u>FOXB2</u> gene in a stem cell, and performing the determination on the basis of the detection result"; and "a differentiation marker selected from an mRNA or a protein derived from a <u>FOXB2</u> gene". The present invention is applicable to the quality management of stem cells and to methods for preparing and isolating differentiated cells. Further, because differentiated cells can be determined at an initial stage of culturing, the present invention is useful for early stage screening of cells and for the quality management of stem cells, and a reduction in culturing period and a reduction in expenditure regarding culture medium costs can be expected. |
