| 发明名称 |
TRANSGENIC NON-HUMAN ORGANISMS WITH NON-FUNCTIONAL TSPO GENES |
| 摘要 |
The present invention relates to transgenic animal models. Specifically, the present invention relates to transgenic animal models for applications associated with TSPO-related normal physiology, diseases and disorders. The present invention features a transgenic nonhuman animal comprising cells with at least one copy of a non-functional, endogenous TSPO gene. Also disclosed are compounds for investigating or modulating TSPO-related functions. |
| 申请公布号 |
US2016050895(A1) |
申请公布日期 |
2016.02.25 |
| 申请号 |
US201414775650 |
申请日期 |
2014.03.13 |
| 申请人 |
AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANIZATION ;THE UNIVERSITY OF SYDNEY |
发明人 |
BANATI Richard;LIU Guo Jun;MIDDLETON Ryan |
| 分类号 |
A01K67/027;G01N33/50 |
主分类号 |
A01K67/027 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1: A transgenic, non-human animal comprising genetically engineered cells with at least one copy of a non-functional, endogenous translocator protein (TSPO) gene. |
| 地址 |
Lucas Heights, New South Wales AU |
