METHODS OF TREATING PROLIFERATIVE DISEASES

摘要

Provided herein are methods of administering N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, or a pharmaceutically acceptable salt or solvate thereof, to human patients, including a specific patient population. Specifically, dosing, dosing schedules or dosing regimens are provided herein. Methods of treating proliferative diseases or FLT-3 mediated diseases in humans are also provided.

主权项

1. A method of treating a proliferative disease in a patient, which comprises administering to the mammal having or suspected to have the proliferative disease, a therapeutically effective amount of the compound of Formula I:or a pharmaceutically acceptable salt or solvate thereof, wherein the therapeutically effective amount is at least about 12 mg per day, and wherein the compound is administered on an empty stomach.