发明名称 |
BLOOD-BRAIN BARRIER (BBB) PENETRATING DUAL SPECIFIC BINDING PROTEINS FOR TREATING BRAIN AND NEUROLOGICAL DISEASES |
摘要 |
Engineered agents or multivalent and multispecific binding proteins capable of penetrating the cells or tissue of the blood-brain barrier (BBB) are provided, along with methods of making and uses in the prevention, diagnosis, and/or treatment of disease. |
申请公布号 |
WO2015191934(A8) |
申请公布日期 |
2016.02.25 |
申请号 |
WO2015US35441 |
申请日期 |
2015.06.11 |
申请人 |
ABBVIE INC. |
发明人 |
HANZATIAN, DENISE KARAOGLU;GOODEARL, ANDREW, D.;MUELLER, BERNHARD KLAUSE;MUELLER, REINHOLD;KLEIN, CORINNA |
分类号 |
C07K16/24;A61K39/00;A61P25/00;A61P25/04;A61P25/10;A61P25/28;A61P35/00;C07K16/28;C07K16/42 |
主分类号 |
C07K16/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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