CELL ASSAY

摘要

The invention relates to a method of measuring one or more thiopurine metabolites in a patient treated with a thiopurine drug, comprising: (i) lysing a test cell derived from said patient in a lysis buffer so as to obtain a cell lysate; and (ii) measuring one or more thiopurine metabolites in said cell lysate, wherein said lysis buffer consists of one or more reagents that do not chemically alter the phosphorylation and/or methylation state of said one or more thiopurine metabolites in said cell lysate.