发明名称 |
RESETTING PLURIPOTENT STEM CELLS |
摘要 |
The invention provides methods and materials for resetting or sustaining a human stem cell in a "naïve" or "ground" state, based on the use of media including combinations of inhibitors. An example naïve culture medium comprises a PKC inhibitor, a MEK inhibitor. Also provided are methods of obtaining or propagating such cells, cells obtained using these methods, and novel culture media, which can be used in these methods. |
申请公布号 |
WO2016027099(A2) |
申请公布日期 |
2016.02.25 |
申请号 |
WO2015GB52431 |
申请日期 |
2015.08.21 |
申请人 |
CAMBRIDGE ENTERPRISE LIMITED |
发明人 |
SMITH, AUSTIN;GUO, GE;TAKASHIMA, YASUHIRO |
分类号 |
C12N5/0735 |
主分类号 |
C12N5/0735 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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