Use of Botulinum Toxin for the Treatment of Cerebrovascular Disease, Renovascular and Retinovascular Circulatory Beds

摘要

Methods of using botulinum toxin based pharmaceuticals are disclosed. The methods cause vasodilatation and decreased flow resistance of certain vascular beds for the purpose of increasing blood flow to a region in order to positively impact deterioration from a number of diseases.

主权项

1. A method of increasing cerebral blood flow which effects a benefit to a central nervous system disease comprising steps of:
a. identifying a subject with an impairment of cerebral blood flow or a patient who is at high risk for developing an impairment in cerebral blood flow; b. injecting a botulinum toxin preparation within a defined dose range into extra cranial region of the head or neck; c. allowing the botulinum toxin to spread within the deep brain structure and cause increased cerebral blood flow; d. Thereby preventing progression or enhancing recovery from cerebrovascular disease.