| 发明名称 |
METHODS OF TREATMENT OF CARDIAC ARRHYTHMIAS USING VANOXERINE AND MODIFICATION OF DIET |
| 摘要 |
Disclosed embodiments are related to methods of treatment of cardiac arrhythmias comprising administration of vanoxerine (GBR 12909) in connection with food of a predetermined fat content to modulate the plasma level concentrations of vanoxerine in a patient. |
| 申请公布号 |
US2016051543(A1) |
申请公布日期 |
2016.02.25 |
| 申请号 |
US201414784860 |
申请日期 |
2014.04.25 |
| 申请人 |
CHANRX CORPORATION |
发明人 |
Brown Arthur M. |
| 分类号 |
A61K31/495;A23L1/30;G01N33/94 |
主分类号 |
A61K31/495 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method for administering vanoxerine for treatment of cardiac arrhythmia comprising:
a. administering a first dose of vanoxerine to a patient; b. determining the bioavailability of the patient by measuring the physiological concentration of vanoxerine; c. calculating an effective dose of vanoxerine to be administered with a meal of a pre-determined fat content to be taken concurrently to modify the physiological concentration; and d. administering the effective dose of vanoxerine with the pre-determined meal. |
| 地址 |
Cleveland OH US |
