发明名称 COMBINATION THERAPY FOR PROLIFERATIVE DISORDERS
摘要 Treatment of proliferative diseases with a combination of a b-Raf inhibitor and MDM2 inhibitor.
申请公布号 US2016051525(A1) 申请公布日期 2016.02.25
申请号 US201514806427 申请日期 2015.07.22
申请人 Hoffmann-La Roche Inc. 发明人 HIGGINS Brian;KOLINSKY Kenneth;NICHOLS Gwen;PACKMAN Kathryn;SU Fei
分类号 A61K31/437;A61K31/40;A61K31/496 主分类号 A61K31/437
代理机构 代理人
主权项 1. A method of treating a patient suffering from cancer, comprising administering to the patient, either concomitantly or sequentially: (i) a first component comprising, as an active agent, vemurafenib, or a pharmaceutically-acceptable salt thereof, and (ii) a second component comprising, as an active agent, an MDM2 inhibitor, or a pharmaceutically-acceptable salt thereof; the amount of said active agents being such that the combination thereof is therapeutically effective in the treatment of said cancer.
地址 Nutley NJ US