发明名称 NOVEL FXR (NR1H4) BINDING AND ACTIVITY MODULATING COMPOUNDS
摘要 The present invention relates to compounds which bind to the NR1H4 receptor (FXR) and act as agonists of FXR. The invention further relates to the use of the compounds for the preparation of a medicament for the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and to a process for the synthesis of said compounds.
申请公布号 EP2987532(A1) 申请公布日期 2016.02.24
申请号 EP20150002478 申请日期 2012.07.12
申请人 GILEAD SCIENCES, INC. 发明人 KINZEL, OLAF;STEENECK, CHRISTOPH;KREMOSER, CLAUS
分类号 A61P1/16;A61K31/42;A61P3/10;A61P35/00;C07D261/08;C07D413/12;C07D413/14 主分类号 A61P1/16
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