摘要 |
The present invention provides a heterocyclic compound of formula (I), a pharmaceutically acceptable salt thereof, a prodrug thereof or a hydrate thereof, wherein A, A′ B, D, R1, R2 and R3 are as defined herein, a pharmaceutical composition comprising a compound of formula (I) as an active ingredient, methods of production, and methods of use thereof. Particularly, the present invention provides a compound of formula (I) useful for treating or preventing a disease, condition or disorder associated with protein kinases, preferably Janus Kinase family. |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
VERMA, ASHWANI, KUMAR;NAGASWAMY, KUMARAGURUBARAN;SHARMA, LALIMA;GHOSH, SOMA;KALE, BALKRISHNA, RAMCHANDRA;MONDAL, ANIRUDDHA;SRIVASTAVA, PUNIT, KUMAR;DASTIDAR, SUNANDA, GHOSH;MIYAUCHI, RIE;MURATA, TAKESHI;ISHIZAKI, MASAYUKI;NAGAMOCHI, MASATOSHI;IIMURA, SHIN;MOMIN, RIJWAN, JAFFER;WAGH, PRADIP, BALU;PANSARE, SONALI, NANASAHEB;MARKAD, PRAMOD, RAOSAHEB;KHAIRNAR, YOGESH, BALASAHEB |