| 发明名称 |
METHOD OF PRODUCING RECOMBINANT IDURONATE-2-SULFATASE |
| 摘要 |
The present invention provides, among other things, methods and compositions for large-scale production of recombinant I2S protein using suspension culture of mammalian cells in serum-free medium. In particular, the present invention uses mammalian cells co-express a recombinant I2S protein and a formylglycine generating enzyme (FGE). |
| 申请公布号 |
EP2867367(A4) |
申请公布日期 |
2016.02.24 |
| 申请号 |
EP20130810106 |
申请日期 |
2013.06.28 |
| 申请人 |
SHIRE HUMAN GENETIC THERAPIES, INC. |
发明人 |
ZHANG, CHUN;BOLDOG, FERENC |
| 分类号 |
C12P21/02 |
主分类号 |
C12P21/02 |
| 代理机构 |
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