发明名称 |
PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR RADIATION DAMAGE |
摘要 |
An object of the present invention is to provide a preventive and/or therapeutic agent for radiation damage that has a novel mechanism of action and can prevent and alleviate a wide range of symptoms of radiation damage for which no therapeutic measures have been available so far, and moreover, is highly safe to humans. A preventive and/or therapeutic agent for radiation damage comprising a compound represented by the following formula (I) such as 5-aminolevulinic acid (5-ALA) or a salt thereof as an active ingredient can be used to improve the survival rate, improve body weight reduction, and alleviate hematopoietic disorder:
(wherein R 1 represents a hydrogen atom or an acyl group; and R 2 represents a hydrogen atom, a linear or branched alkyl group, a cycloalkyl group, an aryl group, or an aralkyl group). |
申请公布号 |
EP2875812(A4) |
申请公布日期 |
2016.02.24 |
申请号 |
EP20130823261 |
申请日期 |
2013.07.11 |
申请人 |
THE UNIVERSITY OF TOKYO;SBI PHARMACEUTICALS CO., LTD. |
发明人 |
TANAKA, TOHRU;NAKAJIMA, MOTOWO;ABE, FUMINORI;ITO, HIDENORI;TAKAHASHI, KIWAMU;MATSUSHIMA, KOUJI;UEHA, SATOSHI;ABE, JUN |
分类号 |
A61K31/195;A61K31/16;A61K31/197;A61K31/22;A61K31/24;A61K31/555;A61K33/26;A61K45/00;A61K45/06;A61P7/00;A61P39/00;A61P43/00 |
主分类号 |
A61K31/195 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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