发明名称 ANTIGEN BINDING PROTEINS TO PROPROTEIN CONVERTASE SUBTILISIN KEXIN TYPE 9 (PCSK9)
摘要 Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.
申请公布号 EP2215124(B1) 申请公布日期 2016.02.24
申请号 EP20080798550 申请日期 2008.08.22
申请人 AMGEN INC. 发明人 JACKSON, SIMON, MARK;WALKER, NIGEL PELHAM, CLINTON;PIPER, DEREK, EVAN;SHAN, BEI;SHEN, WENYAN;CHAN, JOYCE CHI, YEE;KING, CHADWICK, TERENCE;KETCHEM, RANDAL, ROBERT;MEHLIN, CHRISTOPHER;CARABEO, TERESA, ARAZAS;CAO, QIONG
分类号 C07K16/40;A61K31/22;A61K31/366;A61K31/40;A61K31/405;A61K31/44;A61K31/47;A61K31/505;A61K31/66;A61K39/00;A61K39/395;A61K45/06;A61P3/06;C12N15/113 主分类号 C07K16/40
代理机构 代理人
主权项
地址