| 发明名称 | Methods of treating or preventing rheumatic disease | ||
| 摘要 | The present disclosure provides a method for treating or preventing a rheumatic disease, comprising administering a population of cells enriched for STRO-1+ cells and/or progeny thereof and/or soluble factors derived therefrom. | ||
| 申请公布号 | US9265796(B2) | 申请公布日期 | 2016.02.23 |
| 申请号 | US201214130647 | 申请日期 | 2012.07.04 |
| 申请人 | MESOBLAST, INC. | 发明人 | Ghosh Peter;Itescu Silviu |
| 分类号 | A01N63/00;A61K35/28;C12N5/0775 | 主分类号 | A01N63/00 |
| 代理机构 | Cooper & Dunham LLP | 代理人 | White John P.;Cooper & Dunham LLP |
| 主权项 | 1. A method for treating a rheumatic disease in a subject, the method comprising systemically administering to the subject an effective amount of a population of cells enriched for STRO-1+ cells, thereby reducing the level of any one or more of IL-6, TNF-α, IL-17 and/or CDI4+ cells in a joint of the subiect, wherein the STRO-1+ cells are STRO-1+ multipotential cells. | ||
| 地址 | New York NY US | ||