| 发明名称 |
CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF |
| 摘要 |
The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them. |
| 申请公布号 |
CA2674055(C) |
申请公布日期 |
2016.02.23 |
| 申请号 |
CA20072674055 |
申请日期 |
2007.12.28 |
| 申请人 |
MEDAREX, INC. |
发明人 |
SUFI, BILAL;GUERLAVAIS, VINCENT;CHEN, LIANG;GANGWAR, SANJEEV;ZHANG, QIAN;PASSMORE, DAVID B. |
| 分类号 |
C07D403/14;C07D405/14;C07H17/02 |
主分类号 |
C07D403/14 |
| 代理机构 |
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