| 发明名称 |
moduladores de cassete de ligação a atp |
| 摘要 |
Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention. |
| 申请公布号 |
BRPI0921234(A2) |
申请公布日期 |
2016.02.23 |
| 申请号 |
BR2009PI21234 |
申请日期 |
2009.11.06 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORARTED |
发明人 |
BRIAN BEAR;FREDERICK VAN GOOR;JASON MCCARTNEY;JINGLAN ZHOU;MARK T. MILLER;MEHDI MICHEL DJAMEL NUMA;PETER D. J. GROOTENHUIS;SARA S. HADIDA RUAH |
| 分类号 |
C07D209/08;A61K31/404;A61P3/00;A61P25/00;C07D209/12;C07D209/18;C07D405/12 |
主分类号 |
C07D209/08 |
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