| 发明名称 | Anti-FGFR4 antibodies and methods of use | ||
| 摘要 | The invention provides anti-FGFR4 antibodies and methods of using the same. | ||
| 申请公布号 | US9266955(B2) | 申请公布日期 | 2016.02.23 |
| 申请号 | US201314046659 | 申请日期 | 2013.10.04 |
| 申请人 | Genentech, Inc. | 发明人 | Dennis Mark;Desnoyers Luc;French Dorothy |
| 分类号 | A61K39/395;C07K16/00;C07K16/28;A61K45/06;A61K39/00 | 主分类号 | A61K39/395 |
| 代理机构 | Morrison & Foerster LLP | 代理人 | Morrison & Foerster LLP |
| 主权项 | 1. An isolated antibody that binds to human FGFR4, wherein the antibody comprises (a) HVR-H1 comprising the amino acid sequence of SEQ ID NO:1; (b) HVR-H2 comprising the amino acid sequence of SEQ ID NO:2; (c) HVR-H3 comprising the amino acid sequence of SEQ ID NO:3; (d) HVR-L1 comprising the amino acid sequence of SEQ ID NO:4; (e) HVR-L2 comprising the amino acid sequence of SEQ ID NO:5; and (f) HVR-L3 comprising the amino acid sequence of SEQ ID NO:6. | ||
| 地址 | South San Francisco CA US | ||