| 摘要 |
Provided are a compound represented by Formula I, a pharmaceutically acceptable salt thereof, or a solvate thereof; and a pharmaceutical composition for cancer treatment and a pharmaceutical composition for a radiation sensitizer for cancer treatment, each pharmaceutical composition including the compound of Formula I, the pharmaceutically acceptable salt thereof, or the solvate thereof:;wherein, in Formula I,—R1 is a C1-C3 alkoxy, ═O, or —OH, and—R2 is a 5- or 6-membered heteroaryl including 1 to 2 hetero atoms selected from nitrogen and oxygen, wherein a carbon of the 5- or 6-memberedheteroaryl is optionally substituted with a C1-C3 alkyl a C1-C3 alkoxy, or hydroxy. |
| 主权项 |
1. A compound of Formula I, a pharmaceutically acceptable salt thereof, or a solvate thereof: wherein, in Formula I, —R1 is a C1-C3 alkoxy, ═O or —OH, and —R2 is 2H-1,2-oxazine-5-yl, 6H-1,2-oxazine-5-yl, 2H-1,3-oxazine-5-yl, 4H-1,3-oxazine-5-yl, isoxazole-4-yl, or oxazole-4-yl, which is optionally substituted with a C1-C3 alkyl, a C1-C3 alkoxy, or hydroxy, wherein the compound of Formula I excludes N-[2-[[(3,5-dimethyl-4-isoxazolyl)methyl]thio]-6-benzothiazolyl]-4-methoxy-cyclohexanecarboxamide. |
