| 发明名称 | Siglec-9 binding agents | ||
| 摘要 | The present invention relates to agents capable of binding sialic acid-binding immunoglobulin-like lectin-9 (Siglec-9) and their use in the treatment of cell proliferation and differentiation disorders. Furthermore, the present invention provides associated pharmaceutical formulations and methods. | ||
| 申请公布号 | US9265826(B2) | 申请公布日期 | 2016.02.23 |
| 申请号 | US201313796958 | 申请日期 | 2013.03.12 |
| 申请人 | University Court of the University of Dundee | 发明人 | Crocker Paul Richard;Biedermann Bjoern;Bowen David |
| 分类号 | A61K39/395;A61K47/48;C07K16/28;G01N33/50;G01N33/574;A61K31/70;A61K38/02;A61K38/00 | 主分类号 | A61K39/395 |
| 代理机构 | Beusse Wolter Sanks & Maire, PLLC | 代理人 | Beusse Wolter Sanks & Maire, PLLC ;Molinelli Eugene |
| 主权项 | 1. A method of treating a subject having a Siglec-9-expressing cell proliferation and/or differentiation disorder comprising administering to said subject an effective amount of an anti-Siglec-9 antibody comprising a cytotoxic agent. | ||
| 地址 | Dundee GB | ||