发明名称 |
RAMAN QUANTIFICATION METHOD OF CANCER-RELATED SUBSTANCE |
摘要 |
[Problem] To provide a Raman quantification method for measuring cancer cell-derived free DNA. [Solution] This Raman quantification method is characterized by involving a step for preparing a biochip having a mesocrystal region of a silver oxide containing peroxide silver, adding blood serum or biological sample solution dropwise onto the mesocrystal region of said biochip, selectively adsorbing the cancer-related substance having a positive charge in the sample, irradiating the adsorbed cancer-related substance with a laser and detecting Raman scattering therefrom, wherein the cancer illness is determined on the basis of the intensity of the surface-enhanced Raman spectroscopy (SERS). In the carbon-specific D band and G band in the Raman scattering spectrum, a characteristic peak spectrum of the cancer-related substance can be detected in the proximity of the methyl group-characteristic 2900cm-1. |
申请公布号 |
PH12015502537(A1) |
申请公布日期 |
2016.02.22 |
申请号 |
PH12015502537 |
申请日期 |
2015.11.05 |
申请人 |
ITO, HIROAKI;MYTECH CO., LTD. |
发明人 |
ITO, HIROAKI;HASEGAWA, YUKI;HASEGAWA, KATSUYUKI |
分类号 |
G01N21/65;G01N33/543;G01N33/68 |
主分类号 |
G01N21/65 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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