Drug products in the form of modified release formulations comprising the drug substance (-)-(3aR,4S,7aR)-4-Hydroxy-4m-tolylethynyl-octahydro-indole-1-carboxylic acid methyl ester (AFQ056), as well as processes for making such drug products are 5 provided. The drug products are useful in treating patients with Parkinson's disease and exhibiting L-dopa induced dyskinesia.
申请公布号
PH12015502556(A1)
申请公布日期
2016.02.22
申请号
PH12015502556
申请日期
2015.11.10
申请人
NOVARTIS AG
发明人
GALLI, BRUNO;THOMA, HUBERT;GRANDEURY, ARNAUD;SPICKERMANN, DIRK;PUTZBACH, KARSTEN;MOLL, KLAUS-PETER;UFER, MIKE;GLANTZMANN, JEAN-MARIE;MUELLER-ZSIGMONDY, MARTIN