发明名称 |
COMPOSITIONS AND METHODS FOR ENHANCING ANTIGEN-SPECIFIC IMMUNE RESPONSES |
摘要 |
Methods for treating or preventing recurrence of hyper proliferating diseases, e.g., cancer and persistent viral infections, are described. A method may comprise priming a mammal by administering to the mammal an effective amount of a nucleic acid composition encoding an antigen or a biologically active homolog thereof and boosting the mammal by administering to the mammal an effective amount of an oncolytic virus comprising a nucleic acid encoding the antigen or the biologically active homolog thereof. |
申请公布号 |
WO2016025295(A1) |
申请公布日期 |
2016.02.18 |
申请号 |
WO2015US44050 |
申请日期 |
2015.08.06 |
申请人 |
THE JOHNS HOPKINS UNIVERSITY |
发明人 |
WU, TZYY-CHOOU;HUNG, CHIEN-FU;RODEN, RICHARD |
分类号 |
A61K35/76;A61P35/00;A61P37/04;C12N15/33 |
主分类号 |
A61K35/76 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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