发明名称 |
NOVEL CRYSTALLINE FORMS OF A BACE INHIBITOR, COMPOSITIONS, AND THEIR USE |
摘要 |
The present invention provides a novel synthesis of verubecestat, and two novel crystalline forms of verubecestat, as well as pharmaceutically acceptable compositions thereof, each of which may be useful in treating, preventing, ameliorating, and/or delaying the onset of an Aβ pathology and/or a symptom or symptoms thereof. Non-limiting examples of such Aβ pathologies, including Alzheimer's disease, are disclosed herein. |
申请公布号 |
WO2016025364(A1) |
申请公布日期 |
2016.02.18 |
申请号 |
WO2015US44418 |
申请日期 |
2015.08.10 |
申请人 |
MERCK SHARP & DOHME CORP.;KAZAKEVICH, IRINA;TRZASKA, SCOTT;FENG, TAO |
发明人 |
KAZAKEVICH, IRINA;TRZASKA, SCOTT;FENG, TAO |
分类号 |
C07D285/16 |
主分类号 |
C07D285/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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