| 发明名称 |
BICYCLIC SULFONAMIDE COMPOUNDS AS SODIUM CHANNEL INHIBITORS |
| 摘要 |
The present invention provides compounds of Formula I,;;and pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav1.7. The compounds are useful for the treatment of diseases associated with the activity of sodium channels such as pain disorders and itch. Also provided are pharmaceutical compositions containing compounds of the present invention. |
| 申请公布号 |
US2016046626(A1) |
申请公布日期 |
2016.02.18 |
| 申请号 |
US201514920833 |
申请日期 |
2015.10.22 |
| 申请人 |
AMGEN INC. |
发明人 |
WEISS Matthew;BOEZIO Alessandro;BOEZIO Christiane;BUTLER John R.;CHU-MOYER Margaret Yuhua;DIMAURO Erin F.;DINEEN Thomas;GRACEFFA Russell;GUZMAN-PEREZ Angel;HUANG Hongbing;KREIMAN Charles;LA Daniel;MARX Isaac E.;MILGRAM Benjamin Charles;NGUYEN Hanh Nho;PETERSON Emily Anne;VAIDA Karina R.;SPARLING Brian |
| 分类号 |
C07D471/04;C07D417/12;C07D413/14;C07D413/12;C07D401/12 |
主分类号 |
C07D471/04 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
Thousand Oaks CA US |
