An absorbent wound dressing comprises a hydrophilic porous substrate and polymer- stabilized silver nanoparticles distributed throughout the porous substrate. The silver nanoparticles have a particle size d5o in the range of about 45 nm to about 85 nm and the silver nanoparticles are present in the substrate in an amount of about 0.16% to about 1.5 % by weight of the total weight of the substrate. The wound dressing produces a 7-day log reduction of 4 or more for bacteria in accordance with the Modified AATCC Test Method 100. The wound dressing is also non-cytotoxic in accordance with ISO 10993-5 standard procedure for medical device cytotoxicity assessment.
申请公布号
WO2016025770(A1)
申请公布日期
2016.02.18
申请号
WO2015US45150
申请日期
2015.08.13
申请人
ESSENTRA POROUS TECHNOLOGIES CORP.
发明人
JAYAKODY, CHANDRASIRI;JOLES, ANTHONY, J.;SRINIVASAN, RAMESH;STOLTZ, GEOFFREY, M.