发明名称 |
MICRONEEDLES WITH IMPROVED OPEN CHANNEL CROSS-SECTIONAL GEOMETRIES. |
摘要 |
In one aspect a drug delivery device may include a reservoir containing a liquid drug formulation and a microneedle assembly in fluid communication with the reservoir. The microneedle assembly may include a plurality of microneedles, with each microneedle defining an open channel for receiving a drug formulation. The open channel may have a normalized hydraulic radius ranging from about 0.1 to about 0.8. The open channel may also have a Iiquid-to-solid interfacia! energy and a liquid-to-vapor interfacia! energy when a fixed volume of the drug formulation is received therein. In addition, the drug formulation and a cross-sectional geometry of the open channel may be selected and configured such that the liquid- to-solid energy exceeds the liquid-to-vapor energy as the length of the fixed volume of drug formulation is increased within the open channel. |
申请公布号 |
MX2015015273(A) |
申请公布日期 |
2016.02.18 |
申请号 |
MX20150015273 |
申请日期 |
2014.05.20 |
申请人 |
KIMBERLY-CLARK WORLDWIDE, INC. |
发明人 |
RUSSELL F. ROSS;SRIDHAR RANGANATHAN;ANDREW T. BAKER |
分类号 |
A61M37/00;A61M5/158 |
主分类号 |
A61M37/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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