发明名称 |
PROBES FOR IMPROVED MELT DISCRIMINATION AND MULTIPLEXING IN NUCLEIC ACID ASSAYS |
摘要 |
Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of cleavable probes that comprise a ribonucleotide position that is susceptible to endoribonuclease (e.g., RNase H) cleavage in the presence of target nucleic acid molecules. Probes of the embodiments may also comprise non-natural nucleotide linked to a reporter and/or quenching moiety. |
申请公布号 |
CA2956812(A1) |
申请公布日期 |
2016.02.18 |
申请号 |
CA20152956812 |
申请日期 |
2015.08.11 |
申请人 |
LUMINEX CORPORATION |
发明人 |
JOHNSON, SCOTT C.;ARAB, NICOLAS;WHITMAN, DOUG |
分类号 |
C12Q1/68;C07H21/04 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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