发明名称 |
GENETICALLY ENGINEERED BACTERIUM WITH ALTERED CARBON MONOXIDE DEHYDROGENASE (CODH) ACTIVITY |
摘要 |
The invention provides genetically engineered microorganisms with altered carbon monoxide dehydrogenase (CODH) activity and methods related thereto. In particular, the invention provides a genetically engineered carboxydotrophic acetogenic bacterium having decreased or eliminated activity of CODH1 and/or CODH2. In certain embodiments, the bacterium may also have increased activity of CODH/ACS. The invention further provides a method for producing a product by culturing the bacterium in the presence of a gaseous substrate comprising one or more of carbon monoxide, carbon dioxide, and hydrogen. |
申请公布号 |
CA2956204(A1) |
申请公布日期 |
2016.02.18 |
申请号 |
CA20152956204 |
申请日期 |
2015.06.29 |
申请人 |
LANZATECH NEW ZEALAND LIMITED |
发明人 |
KOEPKE, MICHAEL;LIEW, FUNGMIN |
分类号 |
C12N1/21;C12N9/02;C12N15/63;C12P7/06;C12P7/08;C12P7/18 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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