IN VIVO CELL IMAGING

摘要

This disclosure relates to the live imaging of native intracellular proteins in eukaryotic cells, typically mammalian cells, by means of a fluorescent bead coupled to a ligand, a cell penetrating peptide and a cell export peptide adapted to interact with cell secretory proteins to remove non-bound fluorescent beads.

主权项

1. A fluorescent bead comprising:
a ligand that specifically binds an intracellular antigen, a cell membrane penetrating cationic peptide, and a peptide comprising an amino acid sequence that is adapted to interact with the secretory pathway in a cell.