| 发明名称 |
NOVEL CHROMONE ALKALOID DYSOLINE FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISORDERS |
| 摘要 |
The present invention relates to novel chromone alkaloid of formula 1 isolated from the plant Dysoxylum binectariferum. The compound 5,7-dihydroxy-6-(3-hydroxy-1-methylpiperidin-4-yl)-2-methyl-4H-chromen-4-one, is found to be a potential inhibitor of cell growth and proliferation and also inhibits production of pro-inflammatory cytokines. The formulations of this particular compound can be used for treatment of cancer and inflammation.; |
| 申请公布号 |
US2016046611(A1) |
申请公布日期 |
2016.02.18 |
| 申请号 |
US201414783878 |
申请日期 |
2014.03.31 |
| 申请人 |
COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH |
发明人 |
Vishwakarma Ram Asrey;Jain Shreyans Kumar;Bharate Sandip Bibishan;Dar Abid Hamid;Khajuria Anamika;Meena Samdarshi;Bhola Sunil Kumar;Qazi Asif Khurshid;Hussain Aashiq;Sidi Tabasum;Uma Shaanker Ramanan;Ravikanth Gudasalamani;Vasudeva Ramesh;Mohana Kumara Patel;Ganeshaiah Kotiganahalli Narayanagowda |
| 分类号 |
C07D405/04 |
主分类号 |
C07D405/04 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A compound of formula 1 or a pharmaceutically acceptable salt thereof, |
| 地址 |
New Delhi IN |
