Pharmaceutical Combination

摘要

A composition of matter comprising in combination as component (a) at least one 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)phenol compound, and as component (b) at least one antiepileptic, a pharmaceutical formulation and a dosage form comprising said composition of matter, and a method of treating pain, e.g. neuropathic pain, in which components (a) and (b) are administered simultaneously or sequentially to a mammal, whereby component (a) may be administered before or after component (b) and whereby components (a) or (b) are administered to the mammal either via the same or a different pathway of administration.

主权项

1. A composition of matter comprising in combination:
(a) a 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol compound corresponding to formula (I): or a pharmaceutically acceptable salt thereof wherein the 3-(3-dimethylamino-1-ethyl-2-methyl-propyl)-phenol compound corresponding to formula (I) or pharmaceutically acceptable salt thereof is provided in immediate release form, and (b) at least one antiepileptic selected from the group consisting of pregabalin, gabapentin, topiramate, lamotrigine, lacosamide, levetiracetam and retigabine.