METHODS AND COMPOSITIONS OF CARRIER SYSTEMS FOR THE PURPOSE OF INTRACELLULAR DRUG TARGETING
摘要
The present invention relates to a carrier system, a carrier and a pharmaceutical composition comprising a pathogen entry protein or fragment thereof, which specifically binds to a molecule on the surface of a mammalian target cell of said pathogen and which is covalently linked to the surface of said carrier and at least one hydrophilic antipathogenic agent. It further relates to a method of manufacturing a carrier system and the carrier system or the pharmaceutical composition for the use as a medicament.
申请公布号
WO2016024008(A1)
申请公布日期
2016.02.18
申请号
WO2015EP68722
申请日期
2015.08.14
申请人
HELMHOLTZ-ZENTRUM FÜR INFEKTIONSFORSCHUNG GMBH
发明人
LEHR, CLAUS-MICHAEL;LABOUTA, HAGAR IBRAHIM;GORDON, SARAH;CASTOLDI, ARIANNA;MENINA, SARA;GEYER, REBECCA;KOCHUT, ANNIKA;DERSCH, PETRA