主权项 |
1. An isolated peptide comprising or consisting of the amino acid sequence of:(SEQ ID NO: 21)K1K2R3Y4Xaa1Xaa2Xaa3Xaa4L9L10Xaa5Xaa6Xaa7Xaa8Xaa9 wherein: Xaa1 is selected from the group consisting of S (serine), aminoisobutyric acid and an unnatural amino acid; Xaa2 is selected from the group consisting of R (arginine), aminoisobutyric acid and an unnatural amino acid; Xaa3 is selected from the group consisting of E (glutamic acid), aminoisobutyric acid and an unnatural amino acid; Xaa4 is selected from the group consisting of F (phenylalanine), Q (glutamine), A (alanine), aminoisobutyric acid and an unnatural amino acid; Xaa5 is selected from the group consisting of G (glycine), aminoisobutyric acid and an unnatural amino acid; Xaa6 is selected from the group consisting of F (phenylalanine), L (leucine), aminoisobutyric acid, 2-aminobutyric acid and an unnatural amino acid; Xaa7 is absent or selected from the group consisting of Q (glutamine), aminoisobutyric acid and an unnatural amino acid; Xaa8 is absent or selected from, the group consisting of F (phenylalanine), aminoisobutyric acid and an unnatural amino acid; Xaa9 is absent or selected from the group consisting of aminoisobutyric acid and an unnatural amino acid; wherein the peptide comprises at least one peptide-cross linker linking Xaa1, Xaa2, Xaa3 or Xaa4 with Xaa5, Xaa6, Xaa7, Xaa8 or Xaa9. |