VAGUS NERVE STIMULATION AND SUBCUTANEOUS DEFIBRILLATION SYSTEM

摘要

Systems and methods are provided for delivering vagus nerve stimulation and cardioversion/defibrillation therapies to patients for treating chronic heart failure. The vagus nerve stimulation and cardioversion/defibrillation therapies may be provided using a single implantable pulse generator, which can coordinate delivery of the therapies to provide an acute vagus nerve stimulation therapy in advance of delivering cardioversion-defibrillation energy. The implantable neurostimulation system comprises: a pulse generation module comprising a control system, a vagus nerve stimulation (VNS) subsystem, and an implantable cardioverter-defibrillator (ICD) subsystem; a first electrode assembly coupled to the pulse generation module, said first electrode assembly comprising a VNS electrode configured to couple to a vagus nerve; and a second electrode assembly coupled to the pulse generation module, said second electrode assembly comprising a first subcutaneous electrode.