INDOLINE SULFONAMIDE INHIBITORS OF DAPE AND NDM-1 AND USE OF THE SAME
摘要
Indoline sulfonamide compounds that can inhibit DapE and/or bacterial metallo-β- lactamases (MBLs), such as NDM-1, are disclosed. Also disclosed are methods of treating an individual suffering from a bacterial infection using the indoline sulfonamide compounds disclosed herein.
申请公布号
WO2016025637(A1)
申请公布日期
2016.02.18
申请号
WO2015US44915
申请日期
2015.08.12
申请人
LOYOLA UNIVERSITY OF CHICAGO;MARQUETTE UNIVERSITY
发明人
BECKER, DANIEL, PAUL;HOLZ, RICHARD, C.;HEATH, TAHIRAH, K.;REIDL, CORY;STARUS, ANNA;FAST, WALTER