The present invention relates to new proteins that bind to MMP9 and comprise at least one fragment of a heavy chain variable region and/or at least one fragment of a light chain variable region of an antibody. In particular, the MMP9 binding proteins according to the invention are able to neutralize MMP9 activity and are useful in the prevention and/or treatment of inflammatory and/or autoimmune diseases or cancers.
申请公布号
EP2985296(A1)
申请公布日期
2016.02.17
申请号
EP20140180765
申请日期
2014.08.13
申请人
CALYPSO BIOTECH SA;MERCK PATENT GMBH
发明人
CHVATCHKO MISSOTTEN, YOLANDE;GOFFIN, LAURENCE;LEGER, OLIVIER;DUNN, STEVEN M.;POWER, CHRISTINE;MAUNDRELL, KINSEY