发明名称 |
Recombinant antibody molecule and its use for target cell restricted T cell activation |
摘要 |
The present disclosure relates to a recombinant antibody molecule, bispecific as well as tri-specific hetero-dimeric antibody molecules, as well as a method for producing the same, its use and a nucleic acid molecule encoding the recombinant antibody molecules. The disclosure in particular provides an antibody molecule that is capable of mediating target cell restricted activation of immune cells. |
申请公布号 |
EP2985294(A1) |
申请公布日期 |
2016.02.17 |
申请号 |
EP20140181060 |
申请日期 |
2014.08.14 |
申请人 |
DEUTSCHES KREBSFORSCHUNGSZENTRUM;JULIUS-MAXIMILIANS-UNIVERSITÄT WÜRZBURG;EBERHARD KARLS UNIVERSITÄT TÜBINGEN |
发明人 |
JUNG, GUNDRAM;SALIH, HELMUT R.;STUHLER, GERNOT;GROSSE-HOVEST, LUDGER;LOCHMANN, BERIT |
分类号 |
C07K16/30;C07K16/28;C07K16/46 |
主分类号 |
C07K16/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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