发明名称 |
Forma de dosificación resistente a la manipulación para opiádes sensibles a la oxidación |
摘要 |
The invention relates to a thermoformed pharmaceutical dosage form having a breaking strength of at least 300 N, said dosage form comprising
- a pharmacologically active ingredient (A),
- a free physiologically acceptable acid (B) in an amount of from 0.001 wt.-% to 5.0 wt.-%, based on the total weight of the pharmaceutical dosage form, and
- a polyalkylene oxide (C) having a weight average molecular weight M w of at least 200,000 g/mol. |
申请公布号 |
ES2560210(T3) |
申请公布日期 |
2016.02.17 |
申请号 |
ES20100736630T |
申请日期 |
2010.07.21 |
申请人 |
Grünenthal GmbH |
发明人 |
BARTHOLOMÄUS, Johannes;GEISSLER, Anja;BERTRAM, Ulrike;GRIESSMANN, Kornelia |
分类号 |
A61K9/20;A61K9/28;A61K31/485 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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