发明名称 Synthetic peptides with a non-narcotic type of analgesic effect
摘要 Synthetic peptides which have non-narcotic type of analgesic action which may be used in medicine and pharmacology as anesthetic anodynes according to the general formula 1 [SEQ ID NO:1] H-XDL-XDL1-XDL2-L-Lys-L-Leu-XDL3-L-Thr-R2 (I) are disclosed.
申请公布号 US9260482(B2) 申请公布日期 2016.02.16
申请号 US201214386675 申请日期 2012.12.07
申请人 发明人 Vlasov Gennady Petrovich;Kotin Arkadiy Mihajlovich
分类号 A61K38/00;C07K7/06 主分类号 A61K38/00
代理机构 Notaro, Michalos & Zaccaria P.C. 代理人 Notaro, Michalos & Zaccaria P.C.
主权项 1. Synthetic peptides of the general formula 1 [SEQ ID NO: 1] H-XDL-XDL1-XDL2-L-Lys-L-Leu-XDL3-L-Thr-R2  (1), where: H is hydrogen, XDL is absence of amino acid or L-Tyr, XDL1 is one of the following amino acids: L-Leu, L-Ala, or D-Ala, XDL2 is one of the following amino acids: D-His, L-Ala or D-ALA, XDL3 is L-Gln; R2 is OMe or NH2, as anesthetic preparations with non-narcotic type of analgesic action.
地址