Compositions for enhancing wound healing containing magnesium and bromide

摘要

The present invention relates to ionic compositions for enhancing wound healing, particularly in the sinonasal cavity. The ionic components of the composition can include potassium, calcium, rubidium, zinc, bromide, and magnesium in an isotonic solution. In other embodiments, the ionic components of the composition can include magnesium, bromide, sulfate, sodium, and chloride. Methods of enhancing wound healing, enhancing sinonasal mucosal healing, promoting mucosal reciliation, and debriding tissue by administering the compositions of the present invention are also presented.

主权项

1. A sterile solution for enhancing wound healing in a subject consisting of:
a therapeutically effective amount of magnesium ions; a therapeutically effective amount of bromide ions; a therapeutically effective amount of sulfate ions; a therapeutically effective amount of sodium ions; a therapeutically effective amount of chloride ions; and a pharmaceutically acceptable carrier wherein the pharmaceutically acceptable carrier is water or aqueous solutions of a hydrophilic polymer.