| 发明名称 | Concentrated, inhalable antibiotic formulation | ||
| 摘要 | A concentrated inhalable formulation of an antibiotic drug such as ciprofloxacin is disclosed. The antibiotic is formulated with sodium acetate and liposome which incorporate antibiotic. The formulation is aerosolized and inhaled for treatment of respiratory tract infections and other medical conditions. | ||
| 申请公布号 | US9259424(B2) | 申请公布日期 | 2016.02.16 |
| 申请号 | US201414552817 | 申请日期 | 2014.11.25 |
| 申请人 | Aradigm Corporation | 发明人 | Cipolla David C.;Blanchard James |
| 分类号 | A61K9/12;A61K9/127;A61K31/496;A61K45/06;A61K9/00;A61K9/50 | 主分类号 | A61K9/12 |
| 代理机构 | Bozicevic, Field & Francis LLP | 代理人 | Bozicevic Karl;Bozicevic, Field & Francis LLP |
| 主权项 | 1. A method of treatment, comprising: aerosolizing a liquid composition to create aerosolized particles; inhaling the aerosolized particles into a patient's lungs; wherein the liquid composition comprises, a free, unencapsulated ciprofloxacin in an aqueous solution at a concentration of about 10 mg/ml or more with sodium acetate; and a liposome-encapsulated ciprofloxacin wherein the liposomes are comprised of cholesterol and hydrogenated soy phosphatidyl-choline. | ||
| 地址 | Hayward CA US | ||